A dosimetric comparison of different radiotherapy modalities for Non-Resected oligometastatic liver Disease.

ABSTRACT:

Purpose

The role of radiotherapy in the context of limited liver metastases is emerging rapidly with a variety of available technical approaches. Here, we provide a dosimetric comparison of three different radiotherapy modalities for non-resected liver metastases.

Methods

This multicentric study included 30 patients previously treated for solitary liver metastases. Interstitial high dose-rate brachytherapy (HDR), stereotactic body radiation therapy (SBRT), and kilovoltage electronic brachytherapy (eBT) with a single dwelling point, as an in this context novel modality, were planned with a 25-Gy single fraction and dosimetrically compared. The primary endpoint was difference in healthy liver tissue exposure. Secondary endpoints included target volume coverage, dose to the sur

SUBMITTER: Dejonckheere CS 

PROVIDER: S-EPMC11937280 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature