Natural infection of Trypanosoma Cruzi in client-owned-dogs from rural Yucatan, Mexico.

ABSTRACT: Dogs play a crucial role in the transmission cycle of Trypanosoma cruzi and their presence in domicile increases the risk of infection in humans. In Yucatán, Mexico previous studies have reported T. cruzi infection in dogs from both rural and urban areas, which we expanded here, to better understand infection dynamics. A total of 186-dogs were screened for T. cruzi infection by PCR and serology. Parasite burden, genotype, immune response, cardiac alterations, and roaming behavior of the dogs were analyzed. The T. cruzi prevalence was 26.8% (50/186). Genotyping of T. cruzi revealed the predominance of TcI parasites, although most dogs (15/25, 60%) harbored mixed infections with additional DTUs including TcII, TcIV, TcV and TcVI. Antibodies against T. cruzi proteins were detected in > 90% of

SUBMITTER: Calderon-Quintal JA 

PROVIDER: S-EPMC11937323 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature