Antibiotic and colistin resistance pattern of <i>Salmonella</i> spp. isolated from pediatric patients with diarrhea in the Southern region of Vietnam.

ABSTRACT:

Background

Salmonella spp. is a prominent causative agent of pediatric diarrhea, with recent research emphasizing the rising concern regarding antimicrobial resistance (AMR), particularly involving colistin, a last-resort antibiotic.

Methods

This study involved the collection of 500 stool samples from children with diarrhea from two tertiary pediatric hospitals in Ho Chi Minh City. Conventional methods were used to isolate Salmonella spp., and antibiotic resistance profiling against seven antibiotics was conducted using the disk diffusion method. Colistin resistance was determined by the microdilution method. Colistin resistance (mcr) genes were detected by PCR assay. A conjugation experiment with a multidrug-resistant Salmonella strain and E.

SUBMITTER: Le NT 

PROVIDER: S-EPMC11937686 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature