All-Cause Mortality and Specific Causes of Death in Autism: A Nationwide Analysis.

ABSTRACT:

Background

Western studies have reported a higher mortality risk in autistic individuals. However, the specific causes of death and the roles of age, sex, and concurrent intellectual disability (ID) remain unclear. This study aimed to analyze the causes of death in autism and the moderating effects of age, sex, and concurrent ID.

Methods

This nationwide population-based study, conducted between 2008 and 2019, identified 64,685 autistic individuals and were age and sex matched with 1,279,174 nonautistic controls. All-cause mortality and specific causes of death were compared between autistic and nonautistic controls. The modifying effects of age, sex, and concurrent ID were also examined.

Results

The risk of all-cause mortality (hazard ratio = 2.28) is higher in autist

SUBMITTER: Wu CS 

PROVIDER: S-EPMC11937764 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature