The prevalence of rotavirus infection among Congolese children younger than 5 years hospitalized for gastroenteritis 10 years after introduction of rotavirus vaccination.

ABSTRACT:

Objectives

Rotavirus A (RVA) remains the primary cause of acute severe gastroenteritis associated with high rates of childhood hospitalization and mortality worldwide. The prevalence of RVA infection varies within low-income countries. In addition, its genetic diversity may vary among regions and may affect its prevalence. To control the emergence of new strains of RVA circulating in the Republic of Congo, it is essential to know the diversity of both G and P genotypes, which could render the vaccine less effective. Therefore, this study aimed to determine the prevalence and genotype diversity of RVA strains in children who were hospitalized, whether vaccinated or not. Moreover, the potential risk factors of disease severity are identified.

Methods

The study was conducted fr

SUBMITTER: Mboungou CLD 

PROVIDER: S-EPMC11938071 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature