Risk of myocardial infarction and stroke following bloodstream infection: a population-based self-controlled case series.

ABSTRACT:

Background

Cardiovascular disease (CVD) events triggered by inflammation are an underappreciated and poorly quantified cause of morbidity and mortality in patients with bloodstream infections (BSIs). We aimed to determine the risk of myocardial infarction (MI) and stroke after BSI.

Methods

This self-controlled case series study was conducted within the Secure Anonymised Information Linkage Databank, containing anonymised population-scale electronic health record data for Wales, UK. We included adults with community-acquired BSI between 2010 and 2020. MI and stroke were determined from International Classification of Disease Version 10 coded admissions. Predefined risk periods after BSI were compared with the baseline period using pseudo-Poisson regression adjusted for age. M

SUBMITTER: Underwood J 

PROVIDER: S-EPMC11938248 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature