Evaluation of affine fiber kinematics in porcine tricuspid valve leaflets using polarized spatial frequency domain imaging and planar biaxial testing.

ABSTRACT: Collagen fibers are the primary load-bearing microstructural constituent of bodily soft tissues, and, when subjected to external loading, the collagen fibers reorient, uncrimp, and elongate. Specific to the atrioventricular heart valve leaflets, the collagen fiber kinematics form the basis of many constitutive models; however, some researchers claim that modeling the affine fiber kinematics (AFK) are sufficient for accurately predicting the macroscopic tissue deformations, while others state that modeling the non-affine kinematics (i.e., fiber uncrimping together with elastic elongation) is required. Experimental verification of the AFK theory has been previously performed for the mitral valve leaflets in the left-side heart; however, this same evaluation has yet to be performed for the mo

SUBMITTER: Ross CJ 

PROVIDER: S-EPMC11938547 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature