Persistent influence of past obesity on current adiponectin levels and mortality in patients with type 2 diabetes.

ABSTRACT:

Background/aims

Adiponectin, a hormone primarily produced by adipocytes, typically shows an inverse relationship with body mass index (BMI). However, some studies have reported a positive correlation between the two. Thus, this study aimed to examine the relationship between adiponectin level and BMI in diabetic patients, focusing on the impact of past obesity on current adiponectin levels.

Methods

We conducted an observational study analyzing data from 323 diabetic patients at Kyungpook National University Hospital. Based on past and current BMIs, participants were categorized into never-obese (nn, n = 106), previously obese (on, n = 43), and persistently obese (oo, n = 73) groups based on a BMI threshold of 25 kg/m2. Adiponectin level and BMI were key variables. Kaplan-Mei

SUBMITTER: Kim MJ 

PROVIDER: S-EPMC11938665 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature