Association of systemic inflammatory biomarkers with ocular disease: a large population-based cross-sectional study.

ABSTRACT:

Background

The aim of this study was to explore the association of systemic inflammatory biomarkers (systemic immune-inflammation (SII) index and systemic inflammatory response index (SIRI)) with the prevalence of ocular disease in the general population of the United States (U.S.).

Methods

We conducted a cross-sectional study of subjects in the National Health and Nutrition Examination Survey 2005-2008 years. For the analysis of the association of SII index, and SIRI with the prevalence of ocular disease (glaucoma, cataract, age-related macular degeneration (ARMD), and diabetic retinopathy), the restricted cubic spline (RCS) plot, multivariable logistic regression models, and subgroup analysis were performed.

Results

There was a total of 5377 individuals. As shown by

SUBMITTER: Wang X 

PROVIDER: S-EPMC11938706 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature