Genomic alterations of marine yeast Scheffersomyces spartinae under spontaneous and mutagenic conditions.

ABSTRACT:

Background

Understanding the mechanisms of genetic evolution in marine yeasts is essential for their ecological and biotechnological applications. Scheffersomyces spartinae, an ascomycetous yeast species, characterized by its remarkable robustness and carbon source utilization capability, has garnered significant attention for its biotechnological potential.

Results

In this study, we investigated the spontaneous and induced genomic alterations of the marine yeast S. spartinae under various conditions. Through mutation accumulation experiments combined with whole-genome sequencing, we revealed that the rates of spontaneous single nucleotide variations and small insertions and deletions were 6.3 × 10⁻¹¹ and 1.4 × 10⁻¹¹ per base pair per cell division, respectively, in S. spart

SUBMITTER: Bai YT 

PROVIDER: S-EPMC11938759 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature