The value of ¹⁸F-FDG PET/CT and ¹⁸F-DOPA PET/CT in determining the initial surgical strategy of patients with medullary thyroid cancer : Preoperative PET/CT imaging for medullary thyroid cancer.

ABSTRACT:

Background

While total thyroidectomy with central neck dissection (CND) is standard for medullary thyroid cancer (MTC), performing a lateral neck dissection (LND) depends on locoregional metastatic spread and is usually decided per individual. This study evaluated the utility of preoperative PET/CT in staging patients at diagnosis and guiding the initial surgical plan, while also exploring the value of neck ultrasound, MRI, and CT.

Methods

All MTC patients from two tertiary hospitals (2000 - 2020) were identified from two retrospective databases. All reports of neck ultrasounds, MRIs, CTs and PET/CTs < 8 months prior to primary surgery or < 4 months after MTC diagnosis were reviewed. The sensitivity and specificity of each imaging modality for locating locoregional lymph nod

SUBMITTER: Jager EC 

PROVIDER: S-EPMC11938770 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature