Tracking bla_CTX-M transmission through transposable elements in uropathogenic and commensal E. coli.

ABSTRACT:

Aim

To investigate the nucleotide sequences associated with transposable elements carrying bla_CTX-M allelic variants as potential markers for the transmission of antimicrobial resistance genes between domestic animals, humans and the environment.

Materials & methods

We conducted whole-genome sequencing and analyzed the nucleotide sequences of most abundant bla_CTX-M allelic variants (bla_CTX-M-27, bla_CTX-M-55, and bla_CTX-M-65) in commensal Escherichia coli (n = 20) from household members in Quito and uropathogenic E. coli (UPEC) (n = 149) isolated from nine clinics in Quito, Ecuador.

Results

The Ecuadorian commensal E. coli and UPEC displayed identical nucleotide sequences surrounding the bla

SUBMITTER: Guilcazo D 

PROVIDER: S-EPMC11938973 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature