Commercial NIRS May Not Detect Hemispheric Regional Disparity in Continuously Measured COx/COx-a: An Exploratory Healthy and Cranial Trauma Time-Series Analysis.

ABSTRACT: Continuous metrics of cerebral autoregulation (CA) assessment have been developed using various multimodal cerebral physiological monitoring devices. However, CA regional disparity remains unclear in states of health and disease. Leveraging existing archived data sources, we preliminarily evaluated regional hemispheric disparity in CA using the near infrared spectroscopy (NIRS)-derived cerebral oximetry index (COx/COx-a). Along with bilateral NIRS, regional cerebral oxygen saturation, arterial blood pressure, cerebral perfusion pressure, and bilateral COx/COx-a were derived using three different temporal resolutions-10 s, 1 min, and 5 min-based on non-overlapping mean values. The regional disparity between hemispheres was evaluated based on median and median absolute deviation. Further, pa

SUBMITTER: Sainbhi AS 

PROVIDER: S-EPMC11939202 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature