Isolation of <i>vanA</i>-Mediated Vancomycin-Resistant <i>Enterococcus faecalis</i> (ST1912/CC116) and <i>Enterococcus faecium</i> (ST80/CC17), <i>optrA</i>-Positive Linezolid-Resistant <i>E. faecalis</i> (ST32, ST1902) from Human Clinical Specimens in Bangladesh.

ABSTRACT:

Background/objectives

Enterococcus is one of the major nosocomial pathogens. The present status of antimicrobial resistance determinants and virulence factors was analyzed for current Enterococcus causing infectious diseases in Bangladesh.

Methods

Clinical isolates of Enterococcus recovered from various specimens in a tertiary care hospital were analyzed. Antimicrobial susceptibility was measured by a broth microdilution test, and resistance genes/virulence factors were detected by uniplex/multiplex PCR, along with sequencing analysis as required. The sequence type (ST) of E. faecalis and E. faecium was identified based on a multilocus sequence typing (MLST) scheme.

Results

For a one-year period, a total of 143 isolates (135 E. fa

SUBMITTER: Roy S 

PROVIDER: S-EPMC11939402 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature