<i>Escherichia coli</i> in Brazilian Poultry Fecal Samples: Co-Carriage of Fosfomycin and ESBL Resistance.

ABSTRACT: Background/Objectives: Fosfomycin, a critically important antibiotic, is widely used to treat urinary tract infections (UTIs) caused by multidrug-resistant (MDR) Escherichia coli, particularly those producing extended-spectrum β-lactamases (ESBLs). However, its increasing use in livestock has raised concerns about resistance development and global dissemination. This study investigated fosfomycin resistance in E. coli isolates from 400 fecal samples collected at Brazilian broiler farms. Methods: The samples were tested for their minimum inhibitory concentration (MIC), screened with PCR for specific resistance genes, and selected isolated were whole genome sequenced. Results: Phenotypic resistance to fosfomycin was detected in 19% (75/400) of the isolates,

SUBMITTER: Juscele F 

PROVIDER: S-EPMC11939591 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature