Transcriptomics Reveals the Differences in mRNA Expression Patterns in Yak Uterus of Follicular, Luteal, and Pregnant Phases.

ABSTRACT: The yak, an important livestock mostly living in the Qinghai-Tibet Plateau region, has attracted massive attention due to its reproductive specificity. However, the molecular mechanism regulating yak uterine functions remains to be explored. This study utilized transcriptomics to identify differentially expressed genes (DEGs) in yaks across uteruses undergoing the follicular phase (UFP) (n = 3/group), luteal phase (ULP) (n = 3/group), and pregnant phase (UPP) (n = 3/group), aiming to depict and compare their transcriptomic characteristics. For the UFP and ULP groups, 495 DEGs were identified, including 329 upregulated and 166 downregulated DEGs in group ULP compared to UFP. Advanced analysis indicated that these DEGs between UFP and ULP were primary participants in GO

SUBMITTER: Beng S 

PROVIDER: S-EPMC11939727 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature