Sensitivity of Lumbar Total Joint Replacement Contact Stresses Under Misalignment Conditions-Finite Element Analysis of a Spine Wear Simulator.

ABSTRACT: A novel total joint replacement (TJR) that treats lumbar spine degeneration was previously assessed under Mode I and Mode IV conditions. In this study, we relied on these previous wear tests to establish a relationship between finite element model (FEM)-based bearing stresses and in vitro wear penetration maps. Our modeling effort addressed the following question of interest: Under reasonably worst-case misaligned conditions, do the lumbar total joint replacement (L-TJR) polyethylene stresses and strains remain below values associated with Mode IV impingement wear tests? The FEM was first formally verified and validated using the risk-informed credibility assessment framework established by ASME V&V 40 and FDA guidance. Then, based on criteria for unreasonable misuse outlined in the surgic

SUBMITTER: Kurtz SM 

PROVIDER: S-EPMC11939812 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature