Effects of Difenoconazole on <i>Tubifex tubifex</i>: Antioxidant Activity, Insights from GUTS Predictions, and Multi-Biomarker Analysis.

ABSTRACT: The increasing demand for agricultural products has led to a rise in pesticide use, resulting in the pollution of aquatic habitats and raising significant health concerns for both aquatic life and humans. Difenoconazole, a triazole fungicide, is becoming increasingly popular in agriculture, yet its effects on non-target organisms, such as annelids, are not well understood. This study aimed to investigate the toxicological effects of difenoconazole and assess its potential impact on toxicity biomarkers, using Tubifex tubifex as a model organism, to better understand the ecotoxicity of difenoconazole on freshwater annelids. The 96-h LC₅₀ value of difenoconazole was determined to be 2.68 mg/L. Sublethal concentrations (10% and 20% of the 96-h LC₅₀ value; 0.268 and

SUBMITTER: Saha S 

PROVIDER: S-EPMC11939907 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature