Segmentectomy Versus Wedge Resection for Stage IA Lung Adenocarcinoma-A Population-Based Study.

ABSTRACT:

Background

Sublobar resection (SLR), including segmentectomy and wedge resection (WR), is an alternative to lobectomy for early-stage lung cancer due to its potential benefits in preserving lung function. However, the comparative outcomes between segmentectomy and WR for stage IA lung adenocarcinoma are equivocal. This population-based study aimed to compare overall survival between segmentectomy and WR.

Methods

Data on patients with clinical stage IA lung adenocarcinoma were collected from the Taiwan Cancer Registry between 2011 and 2018. The primary endpoint was overall survival. Further subgroup survival analyses were conducted based on tumor size. Propensity score matching (PSM) was used to balance baseline differences such as age and tumor stage between the two groups.

SUBMITTER: Chiang XH 

PROVIDER: S-EPMC11940408 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature