Low-Cost, Open-Source, High-Precision Pressure Controller for Multi-Channel Microfluidics.

ABSTRACT: Microfluidics is a technology that manipulates liquids on the scales ranging from microliters to femtoliters. Such low volumes require precise control over pressures that drive their flow into the microfluidic chips. This article describes a custom-built pressure controller for driving microfluidic chips. The pressure controller features piezoelectrically controlled pressure regulation valves. As an open-source system, it offers high customizability and allows users to modify almost every aspect. The cost is roughly a third of what similar, alternative, commercially available piezoelectrically controlled pressure regulators could be purchased for. The measured output pressure values of the device vary less than 0.7% from the device's reported pressure values when the requested pressure is

SUBMITTER: Ernits M 

PROVIDER: S-EPMC11940448 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature