Characteristics and Neoplastic Progression in Barrett's Esophagus: A Large Population-Based Study from Iceland.

ABSTRACT: Background: Barrett's esophagus (BE) is a known precursor to esophageal adenocarcinoma (EAC). However, reports on incidence and progression-to-neoplasm rates have been very variable and conflicting. The aims of the study were to evaluate the characteristics of BE and its progression to neoplasm in a large homogeneous population. Methods: This was a retrospective population-based study with patients identified from 11 institutions through the databases in two centralized pathology laboratories. Demographics and relevant clinicopathological features were obtained from medical records among patients with a pathologically confirmed BE by the presence of intestinal metaplasia between 2003 and 2022. Results: A total of 1388 patients were identified with BE: 948 were men (69%

SUBMITTER: Namikawa K 

PROVIDER: S-EPMC11941158 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature