Open, Randomised, Controlled Study to Evaluate the Role of a Dietary Supplement Containing <i>Pelargonium sidoides</i> Extract, Honey, Propolis, and Zinc as Adjuvant Treatment in Children with Acute Tonsillopharyngitis.

ABSTRACT:

Background/objectives

A common reason for a pediatrician's visit is acute tonsillopharyngitis (ATR), which is usually caused by viruses. A dietary supplement comprising Pelargonium sidoides extract, honey, propolis, and zinc was proposed as an effective adjuvant for the management of respiratory tract infections. The study aimed to determine the efficacy of this dietary supplement in conjunction with standard of care (SoC) compared to SoC alone, in a pediatric population affected by ATR.

Methods

This open randomized study (registered on ClinicalTrials.gov: NCT04899401) involved three Romanian sites specialized in pediatric care. The primary endpoints were changes in Tonsillitis Severity Score and the number of patients failing to respond (evaluating the use of ibuprof

SUBMITTER: Cardinale F 

PROVIDER: S-EPMC11941233 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature