Detectability of Iodine in Mediastinal Lesions on Photon Counting CT: A Phantom Study.

ABSTRACT: Background/Objectives: To evaluate the detectability of iodine in mediastinal lesions with photon counting CT (PCCT) compared to conventional CT (CCT) in a phantom study. Methods: Mediastinal lesions were simulated by five cylindrical inserts with diameters from 1 to 12 mm within a 10 cm solid water phantom that was placed in the mediastinal area of an anthropomorphic chest phantom with fat ring (QRM-thorax, QRM L-ring, 30 cm × 40 cm cross-section). Inserts were filled with iodine contrast at concentrations of 0.238 to 27.5 mg/mL. A clinical chest protocol at 120 kV on a high-end CCT (Somatom Force, Siemens Healthineers) was compared to the same protocol on a PCCT (Naeotom Alpha, Siemens Healthineers). Images reconstructed with a soft tissue kernel at 1 mm thickness and a 512

SUBMITTER: Centen JR 

PROVIDER: S-EPMC11941654 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature