Short Exposures to Phosphine Trigger Differential Gene Expression in Phosphine-Susceptible and -Resistant Strains of <i>Tribolium castaneum</i>.

ABSTRACT:

Background/objectives

Phosphine resistance in insects involves a complex interplay of genetic and physiological factors, which are often poorly understood. Resistance to high concentrations of phosphine worldwide poses a formidable challenge for stored-product pest management and affects global food security. Understanding the genetic basis of phosphine resistance in the red flour beetle, Tribolium castaneum, is urgent because of the species' status as a notorious insect pest of stored grains and their resistance to major classes of insecticides. In this study, we take advantage of T. castaneum as a model species for biological and genetic studies.

Methods

To tease apart genetic mutations and the differential expression of genes responding to phosphine intoxica

SUBMITTER: Athanassiou CG 

PROVIDER: S-EPMC11942322 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature