An Exploratory Genomic and Transcriptomic Analysis Between <i>Choloepus didactylus</i> and <i>Homo sapiens</i>.

ABSTRACT: Background/Objectives: Sloths, a group of xenarthran mammals currently comprising six recognized distinct species, have been the focus of much physiological animal research due to their extremely slow metabolisms, deliberate movements, and their status as a species relatively unchanged for over 26 million years. However, despite all the effort aimed at understanding these unique characteristics, the sloth genome remains largely unexplored. Due to the link between genetics and observed traits, such an investigation could potentially lead to insights regarding the genetic basis of unique sloth behaviors and characteristics, such as slow movement, low metabolism, and longevity. Methods: In this exploratory investigation, we performed whole genomic and transcriptomic analysis of

SUBMITTER: Baran A 

PROVIDER: S-EPMC11942560 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature