Genomic Patterns of Homozygosity and Genetic Diversity in the Rhenish German Draught Horse.

ABSTRACT:

Background/objectives

The Rhenish German draught horse is an endangered German horse breed, originally used as working horse in agriculture. Therefore, the objective of this study was to evaluate the breed's genetic diversity using pedigree and genomic data in order to analyze classical and ancestral pedigree-based inbreeding, runs of homozygosity, ROH islands, and consensus ROH.

Methods

We studied the genome-wide genotype data of 675 Rhenish German draught horses and collated pedigree-based inbreeding coefficients for these horses. The final dataset contained 64,737 autosomal SNPs.

Results

The average number of ROH per individual was 43.17 ± 9.459 with an average ROH length of 5.087 Mb ± 1.03 Mb. The average genomic inbreeding coefficient F_ROH was 0.099 ±

SUBMITTER: Sievers J 

PROVIDER: S-EPMC11942601 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature