Transcriptomic Profiling Provides Insight into the Molecular Basis of Heterosis in Philippine-Reared <i>Bombyx mori</i> Hybrids.

ABSTRACT: In the Philippines, Bombyx mori parental strains Lat21 and B221 are crossed to yield NC144 and CN144, which demonstrate hybrid vigor. The molecular basis of the observed vigor in the hybrids is warranted, as it may assist in improving local sericulture programs. This study, therefore, aims to investigate the basis of hybrid vigor and generate molecular resources through whole-silkworm larvae transcriptome sequencing, assembly, and analysis. Differential gene expression was also conducted among the parental strains and hybrids. Assembly of the pre-processed reads was also performed using de novo and reference-based protocols. As expected, the reference-based assembly was better than de novo, based on E90N50, N50, and BUSCO assembly completeness metrics. The Analysis of the differenti

SUBMITTER: Conde MYED 

PROVIDER: S-EPMC11942671 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature