Biochemical and Transcriptomic Analysis Reveals Low Temperature-Driven Oxidative Stress in Pupal <i>Apis mellifera</i> Neural System.

ABSTRACT: Exposure to low temperatures during honeybee development has been shown to impede brain development and affect cognitive function in adult bees. On the other hand, neuronal damage due to oxidative stress has been reported in many cases. Hence, biochemical parameters related to oxidative stress in honeybee pupae brain were determined. The levels of GSH in the pupal brain decreased after 24 h and 48 h of exposure to low temperatures; there were also reduced activities of SOD and CAT enzymes following 48 h of low-temperature treatment compared to the control group. Furthermore, analysis of transcriptome data post-24 h and -48 h low-temperature stress revealed the suppression of the glutathione metabolism and peroxisome pathways in pupal brains. Additionally, expression pattern clustering anal

SUBMITTER: Zhu X 

PROVIDER: S-EPMC11942804 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature