Untargeted Metabolomics and Targeted Phytohormone Profiling of Sweet Aloes (<i>Euphorbia neriifolia</i>) from Guyana: An Assessment of Asthma Therapy Potential in Leaf Extracts and Latex.

ABSTRACT: Background/Objectives:Euphorbia neriifolia is a succulent plant from the therapeutically rich family of Euphorbia comprising 2000 species globally. E. neriifolia is used in Indigenous Guyanese asthma therapy. Methods: To investigate E. neriifolia's therapeutic potential, traditionally heated leaf, simple leaf, and latex extracts were evaluated for phytohormones and therapeutic compounds. Full scan, data-dependent acquisition, and parallel reaction monitoring modes via liquid chromatography Orbitrap mass spectrometry were used for screening. Results: Pathway analysis of putative features from all extracts revealed a bias towards the phenylpropanoid, terpenoid, and flavonoid biosynthetic pathways. A total of 850 compounds were annotated using various

SUBMITTER: Persaud M 

PROVIDER: S-EPMC11943701 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature