Apolipoproteins in Psoriasis: The Effect of Acitretin Treatment and UVB Phototherapy.

ABSTRACT:

Background

Psoriasis is a chronic, multi-system inflammatory disease frequently associated with metabolic syndrome and lipid disturbances. Apolipoproteins, as essential regulators of lipid metabolism, may play a critical role in these metabolic abnormalities, potentially influencing disease severity and systemic inflammation. The aim of this study was to compare serum concentrations of chosen apolipoproteins in patients with psoriasis before and after treatment with acitretin or narrowband UVB (NB-UVB).

Methods

This study was conducted on 39 patients with psoriasis. The concentration of nine apolipoproteins and C-reactive protein was quantified using the Bio-Plex Immunoassay Kit.

Results

The serum concentrations of ApoA2, ApoC1, ApoD, ApoE, and ApoJ were higher in the

SUBMITTER: Mysliwiec H 

PROVIDER: S-EPMC11944098 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature