Hypoglycemic and Hypolipidemic Effects of Triterpenoid Standardized Extract of <i>Agave durangensis</i> Gentry.

ABSTRACT: Diabetes mellitus is a chronic, degenerative, and multifactorial disease characterized by hyperglycemia, and at least 537 million people suffered from diabetes in 2021. Agave durangensis Gentry, a species of agave native to the state of Durango, reports phenolic compounds, flavonols, flavonoids, and saponins and could be an alternative for the treatment of diabetes. The aim of this work was to identify the compounds in the leaves of Agave durangensis Gentry and their potential activity in diabetes. The leaf extract of Agave durangensis Gentry (EAD) was characterized by ultra-performance liquid chromatography-mass spectrometry (UPLC-MS), and different families of bioactive compounds were quantified by analytical methods. Probable pharmacological targets were identified

SUBMITTER: Bermudes-Contreras JD 

PROVIDER: S-EPMC11944376 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature