Genomic, Probiotic, and Functional Properties of <i>Bacteroides dorei</i> RX2020 Isolated from Gut Microbiota.

ABSTRACT:

Background/objectives

Gut microbiota is essential for maintaining host immune homeostasis and has been confirmed to be closely related to some intestinal and extraintestinal diseases. Bacteroides, as the dominant bacterial genus in the human gut, has attracted great attention due to its excellent metabolic activity, but there are few studies on Bacteroides dorei species. In our previous study, a gut commensal strain, Bacteroides dorei RX2020 (B. dorei), was isolated from healthy human feces and exhibited superior flavonoid metabolic activity, prompting further analysis of its uncharacterized genomic features, probiotic potential, safety, and immunomodulatory activity.

Results

The results showed that B. dorei exhibited intrinsic probiotic fu

SUBMITTER: He S 

PROVIDER: S-EPMC11944543 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature