Characterization of Newly Isolated <i>Rosenblumvirus</i> Phage Infecting <i>Staphylococcus aureus</i> from Different Sources.

ABSTRACT: Staphylococcus aureus is a globally significant pathogen associated with severe infections, foodborne illnesses, and animal diseases. Its control has become increasingly challenging due to the spread of antibiotic-resistant strains, highlighting the urgent need for effective alternatives. In this context, bacteriophages have emerged as promising biocontrol agents. This study aimed to characterize the newly isolated Staphylococcus phage CapO46 and evaluate its efficacy in reducing S. aureus in milk. Identified as a new species within the Rosenblumvirus genus, CapO46 exhibited a podovirus-like structure and a small linear dsDNA genome (17,107 bp), with no lysogeny-related, antimicrobial resistance, or virulence genes. Host range assays demonstrated its ability to

SUBMITTER: Cunha PC 

PROVIDER: S-EPMC11945092 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature