The impact of the COVID-19 pandemic on antimicrobial usage: an international patient-level cohort study.

ABSTRACT:

Background

This study aimed to evaluate the trends in antimicrobial prescription during the first 1.5 years of COVID-19 pandemic.

Methods

This was an observational, retrospective cohort study using patient-level data from Bangladesh, Brazil, India, Italy, Malawi, Nigeria, South Korea, Switzerland and Turkey from patients with pneumonia and/or acute respiratory distress syndrome and/or sepsis, regardless of COVID-19 positivity, who were admitted to critical care units or COVID-19 specialized wards. The changes of antimicrobial prescription between pre-pandemic and pandemic were estimated using logistic or linear regression. Pandemic effects on month-wise antimicrobial usage were evaluated using interrupted time series analyses (ITSAs).

Results

Antimicrobials for which

SUBMITTER: Farzana R 

PROVIDER: S-EPMC11945301 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature