Systemic Inflammatory Response Syndrome and Prosthetic Joint Infection.

ABSTRACT:

Background

The development of systemic inflammatory response syndrome (SIRS) criteria leads to increased mortality. Little is known about development of SIRS in patients who have prosthetic joint infection (PJI). We aimed to determine the incidence, risk factors, clinical outcomes, and causative organisms in patients who develop SIRS with PJI.

Methods

We retrospectively identified 655 patients (321 men, 334 women; 382 total hip, 273 total knee) who have hip or knee PJI at 1 institution between July 1, 2015 and December 31, 2020. We formed 2 groups: patients who have SIRS alert (PJI + SIRS) and patients who do not have SIRS alert (PJI). We analyzed clinical outcomes, comorbidities, and operating room culture results.

Results

Of 655 patients, 63 developed SIRS with PJI

SUBMITTER: McConnell ZA 

PROVIDER: S-EPMC11945344 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature