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Effects of plant-based diet on metabolic parameters, liver and kidney steatosis: a prospective interventional open-label study.


ABSTRACT: This interventional single-centre prospective open-label study aims to evaluate the effects of a vegan diet, compared with a vegetarian and omnivorous diet, on metabolic parameters, insulin sensitivity, and liver and kidney steatosis in healthy adults. The study included fifty-three omnivorous participants aged 18-40 years, BMI 18-30 kg/m2, without any chronic disease, chronic medication use, active smoking or significant alcohol consumption. All participants were omnivorous at baseline and selected to continue an omnivorous diet or transition to a vegetarian or vegan diet, with follow-up over 6 months. Anthropometric measurements, biochemical parameters and liver and kidney steatosis were assessed at baseline and after six months using MRI-proton density fat fraction. Primary o

SUBMITTER: Guler Senturk B 

PROVIDER: S-EPMC11946044 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature