<i>Pseudomonas</i> Phage Lydia and the Evolution of the <i>Mesyanzhinovviridae</i> Family.

ABSTRACT: Phage Lydia, a newly isolated siphovirus infecting Pseudomonas aeruginosa, was characterized with respect to its basic kinetic properties and subjected to comparative bioinformatic analysis with related phages. The phage exhibited a restricted host range, with lytic activity observed against 7 of 30 tested isolates. The genome of phage Lydia consists of a 61,986 bp dsDNA molecule and contains 89 predicted genes. Bioinformatic analysis suggests the presence of a DNA modification system, but no apparent genes associated with lysogeny or antibiotic resistance were identified. Taxonomic classification places Lydia within the Mesyanzhinovviridae family, Rabinowitzvirinae subfamily, and Yuavirus genus, with the closest relation to Pseudomonas virus M6. Comprehensive b

SUBMITTER: Troshin K 

PROVIDER: S-EPMC11946847 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature