Unveiling shifts in cervical microbiota composition among Colombian women in the presence of Trichomonas vaginalis: a longitudinal study.

ABSTRACT: Trichomonas vaginalis is a flagellated protozoan affecting human reproductive health. Although bacterial coinfections have been associated with T. vaginalis infection outcomes, pertinent data are scarce. This study was aimed at assessing vaginal bacterial community changes regarding T. vaginalis outcomes (infection, clearance, persistence) during patients' follow-up visits. This was a 1-year follow-up study involving Colombian women who provided two cytological scrapings from the cervix (one at baseline and another at follow-up), having an average 12 ± 1 month follow-up interval. T. vaginalis was detected by conventional PCR (Tvk3/7 and BTU9/2 primers). The Illumina Novaseq PE250-platform was used for assessing microbiota composition. This study involved 66 women (132 samples); 68.2% (n = 

SUBMITTER: Camargo M 

PROVIDER: S-EPMC11946947 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature