Long-term kidney outcomes in survivors of Wilms tumor: a single-center retrospective cohort study.

ABSTRACT:

Background

Several studies have investigated long-term kidney outcomes in survivors of Wilms tumor (WT). However, many have small sample sizes, and there is a wide variation in reported outcomes. The aim of this study is to investigate the long-term kidney outcomes in survivors of WT (S-WT), including those patients considered to be at high risk for poor kidney outcomes, and using updated estimated glomerular filtration rate (eGFR) equations.

Methods

This was a retrospective chart review of 64 patients treated for WT at a single pediatric center. Patients were off treatment for 5 years or more at the time of analysis and were evaluated for decreased kidney function, hypertension, proteinuria, and compensatory hypertrophy of the contralateral kidney.

Results

At a media

SUBMITTER: Reinert S 

PROVIDER: S-EPMC11947031 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature