A practical one-pot synthesis of dehydroalanine esters.

ABSTRACT: A practical one-pot synthesis of various dehydroalanine esters was realized via a Cs₂CO₃-mediated simultaneous esterification/elimination process, starting from commercially available N-protected serines and various haloalkanes. This protocol provided easy access to structurally diverse dehydroalanine-based building blocks, which were successfully applied to construct more complex dehydroalanine derived molecules.

SUBMITTER: Shi Q 

PROVIDER: S-EPMC11947901 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature