Correlation analysis of lumbar disc degeneration characteristics and bone mineral density in patients with osteoporosis based on the Roussouly classification.

ABSTRACT:

Background

Lumbar disc degeneration (LDD), endplate damage, and osteoporosis (OP) are closely linked; however, research on the influence of sagittal alignment on bone mineral density (BMD) and LDD is limited. This study aimed to explore the relationship between BMD, degenerative changes in intervertebral discs (IVDs), and endplate damage in patients with OP based on the Roussouly classification.

Methods

This retrospective study included 150 patients with and 150 without OP. Dual-energy X-ray absorptiometry (DXA) measured L1-4 vertebral BMD. Magnetic resonance imaging (MRI) assessed Pfirrmann grading (as a marker for disc dehydration status) and grading of endplate damage in the L1-S1 segments. The vertebral osteophyte score was evaluated. IVD degeneration and endplate damage

SUBMITTER: Zhao S 

PROVIDER: S-EPMC11948380 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature