Assessment of coronary computed tomography angiography-derived plaque features in the diagnosis of optical coherence tomography-defined vulnerable plaques.

ABSTRACT:

Background

Identification of vulnerable plaque is essential for pre-estimation of the risk of cardiovascular disease (CVD) and stratification of major adverse cardiac events (MACEs) risks. This study aimed to evaluate the diagnostic ability of coronary computed tomography angiography (CCTA)-derived qualitative and quantitative plaque features in detecting optical coherence tomography (OCT)-defined vulnerable plaques.

Methods

A total of 31 patients who underwent both CCTA and OCT were retrospectively included in this study. The results of OCT and CCTA were blindly analyzed on a segment-to-segment comparison. The qualitative and quantitative plaque parameters derived by CCTA were recorded. Univariate analysis and multivariate logistic regression analysis were performed to reve

SUBMITTER: Liu X 

PROVIDER: S-EPMC11948381 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature