Integration of PET/CT parameters and a clinical variable to predict the risk of progression of disease within 24 months (POD24) in follicular lymphoma.

ABSTRACT:

Background

Patients with follicular lymphoma (FL) who experience progression of disease within 24 months (POD24) of receiving first-line therapy had a significantly poorer prognosis than that without early progression. Due to the established prognostic relevance of positron emission tomography/computed tomography (PET/CT) parameters in FL and their clinical accessibility, we aimed to investigate the predictive role of PET/CT metabolism and dissemination parameters in POD24 for FL.

Methods

The POD24 status of 155 patients who underwent PET/CT examinations at initial diagnosis was evaluated. Various baseline characteristics were collected, along with PET/CT-derived parameters, including the maximum tumor dissemination (Dmax), maximum standardized uptake (SUVmax) value, total m

SUBMITTER: Jiang Q 

PROVIDER: S-EPMC11948388 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature