Simultaneous intravascular large B‑cell lymphoma and papillary thyroid carcinoma: A case report.

ABSTRACT: Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of B-cell lymphoma. The concurrence of IVLBCL and papillary thyroid carcinoma (PTC) is extremely rare. A 63-year-old woman was diagnosed with double-expression IVLBCL that presented as a hemophagocytic syndrome, complicated by PTC. IVLBCL was diagnosed by positron emission tomography/computed tomography (PET/CT) before bone marrow biopsy. Immunofixation electrophoresis displayed M proteins positive and IgG kappa light chains that the differential diagnosis should have included both multiple myeloma and IVLBCL. After treatment with rituximab, cyclophosphamide, hydroxydaunorubicin, vincristine, prednisone and etoposide, the patient's cytokine titres and other laboratory indicators returned to normal. PET/CT showed that complete r

SUBMITTER: Liang J 

PROVIDER: S-EPMC11948454 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature