Therapeutic hypothermia in patients with acute myocardial infarction complicated by out-of-hospital cardiac arrest.

ABSTRACT:

Background

There is a lack of data regarding outcomes of therapeutic hypothermia in patients with acute myocardial infarction (AMI) complicated by out-of-hospital cardiac arrest (OHCA). This study aimed to evaluate the effect of therapeutic hypothermia on clinical outcomes in comatose patients after percutaneous coronary intervention (PCI) for AMI following OHCA.

Methods

Using a prospective nationwide registry from 2016 to 2021, we selected 2925 patients with AMI who underwent emergency PCI among 182,508 OHCA cases. These patients were divided into groups receiving hypothermia treatment (n = 624) and those not receiving hypothermia treatment (n = 2301). The primary endpoint was in-hospital mortality, and secondary endpoints were mortality rate at 24 h and neurological outcom

SUBMITTER: Lee OH 

PROVIDER: S-EPMC11948712 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature