Serum CA125: a prognostic biomarker for mortality in chronic heart failure.

ABSTRACT:

Objective

To examine the relationship between serum Carbohydrate Antigen 125 (CA125) levels and long-term mortality in Chronic Heart Failure (CHF) patients and to assess its predictive value as a biomarker.

Methods

This was a retrospective cohort study. We reviewed the medical records of 4,442 consecutive patients admitted to the First Affiliated Hospital of Xinjiang Medical University with a diagnosis of CHF since July 2012. After applying inclusion and exclusion criteria, 1,413 patients with available CA125 level measurements were included. The patients were categorized into three groups based on ejection fraction: HFrEF, HFmrEF, and HFpEF. Demographic details, comorbidities, and laboratory parameters were collected. CA125 levels were measured using an automated chemilumin

SUBMITTER: Tuersun R 

PROVIDER: S-EPMC11948815 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature