Zoonotic potential of uropathogenic Escherichia coli lineages from companion animals.

ABSTRACT: Escherichia coli is responsible for urinary tract infections (UTI) in humans and pets. This study aims to provide data on the virulome and resistome of E. coli strains isolated during bacteriuria in companion animals and to assess their zoonotic potential. 135 E. coli strains prospectively collected from urine samples of 44 cats and 91 dogs in three French veterinary teaching hospitals were analyzed via antibiotic susceptibility tests and whole genome sequencing. Phylogroup B2 was overrepresented and several sequence types (STs) associated with human extra-intestinal pathogenic E. coli (ExPEC) were found. These included ST12, ST127 and ST141 (8 strains each), which were characterized by genetic homogeneity, and ST73 (23 strains) which contained several serotype-delineated sublineages with

SUBMITTER: Jousserand N 

PROVIDER: S-EPMC11948896 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature