Association of spontaneous abortion and lifestyle with diabetes mellitus in women: a cross-sectional study in UK Biobank.

ABSTRACT:

Background

Spontaneous abortion has been associated with higher risk of type 2 diabetes mellitus (T2DM) and gestational diabetes mellitus (GDM), while the evidence remains equivocal. This study aimed to examine the association between spontaneous abortion and the risk of T2DM and GDM, and assesses whether lifestyle factors modified this association.

Methods

This cross-sectional study used data from the UK Biobank, recruiting 170 599 ever-pregnant women from 22 assessment centers in England, Scotland, and Wales between 2006 and 2010. History of spontaneous abortion was self-reported and was confirmed by using medical records, categorized as none, 1, 2, or ≥3 spontaneous abortions. The primary outcomes, T2DM and GDM, were ascertained from medical records using ICD-10 codes. Mu

SUBMITTER: Liu S 

PROVIDER: S-EPMC11948972 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature