Occupational benzene exposure and risk of kidney and bladder cancers: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Benzene is recognized as leukemogenic. However, the association between it and solid cancers has been the subject of less investigation. We aim to conduct a systematic review and meta-analysis to evaluate the association between occupational exposure to benzene and the risk of urinary tract cancer, including kidney and bladder.

Methods

We included 41 cohort and case-control studies listed in the most recent International Agency for Research on Cancer (IARC) Monograph on benzene exposure and the result of a literature review to identify more recent studies. Forest plots of relative risk (RR) were constructed for kidney, bladder, and urinary tract cancer overall. A random-effects model was used to address heterogeneity between studies. Stratified analyses were con

SUBMITTER: Seyyedsalehi MS 

PROVIDER: S-EPMC11949222 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature