Exploring Aachen minipigs as in vivo model for human intracranial studies: Focus on hind limb artery diameters.

ABSTRACT: Endovascular methods for stroke treatment have become increasingly popular in recent years and continue to be improved. Pigs serve as in vivo models in endovascular stroke research for device testing and training purposes. Due to a network of small vessels between the cerebral and intracranial arteries, called rete mirabile, catheterization of the brain-supplying arteries in pigs is impossible. Alternatively, various porcine arteries can be used. Aachen minipigs have become more popular in the last years, but specific data on their vascular diameters are limited to the forelimb arteries. Therefore, the aim of our study was to assess diameters of porcine hind limb arteries in eight female Aachen minipigs (weight of 47.08 kg ±  4.58 kg and age of 17 to 21 months), focusing on the internal il

SUBMITTER: Bender L 

PROVIDER: S-EPMC11949345 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature